PFT: Agent says Belcher was 'happy, proud father'

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This year, the fines imposed by the NFL against players who have done things on the field they arguably shouldn?t have done have taken on a bizarre level of specificity.

The specificity comes not on a case-by-case basis, but from the agreement reached by the league and the NFLPA regarding the minimum amounts for various infractions.

For physical contact with an official, for example, the minimum player fine is $26,250 on a first offense. Verbal or non-physical offenses against officials entail a less specific $21,000 fine for a first offense.

For striking, kicking, or kneeing an opponent, the minimum for a first offense is $7,875.

Horse collar, first offense?? $15,750 minimum.

Face mask, late hit, low block, chop block, taunting?? $7,875 minimum.

Leg whip, roughing the passer?? $15,750 minimum.

Spearing, hit on defenseless player, blindside block, impermissible helmet use?? $21,000 minimum.

Fighting?? $26,250 minimum.

Excessive profanity or other unsportsmanlike conduct triggers a minimum fine of $10,500.

Foreign substances on the uniform/body or failure to wear a chin strap results in a minimum fine of $7,875.

Throwing a football into the stands or personal messages on the uniform draw a minimum fine of $5,250.

For second offenses, all minimum fines double.

Remember, these are minimum fines.? The league office can go higher, if it chooses.

The fines for on-field misconduct between players are subject to appeal to Ted Cottrell or Art Shell, former coaches who have been jointly appointed and who are jointly paid by the NFL and the NFLPA.? And while the initial fines are disclosed by the league on request, announcements regarding reductions rarely if ever are made.

Some believe that the fines should be based on a percentage of player salary or cap number.?? Until that happens (and it possibly never will), specific amounts negotiated by the NFL and the NFLPA will apply to all players, regardless of how much or how little they make.

Source: http://profootballtalk.nbcsports.com/2012/12/01/agent-remembers-jovan-belcher-as-a-happy-proud-father/related/

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Daily news roundup: November 30, 2012

How signal molecules for formation of various cell types are controlled

ScienceDaily (Nov. 30, 2012) ? The regulation of important signal molecules that are critical for the formation of various cell types can be influenced by a chemically produced variant of indirubin, a natural material used in traditional Chinese medicine. This was shown by scientists from Heidelberg University, Kaiserslautern and Jena. The researchers were also able to demonstrate for the first time that these signal molecules in the cell -- regulatory SMAD proteins -- are not only controlled through regulation of their activation but also through the available quantity of signal molecules in the non-activated state. Because cellular differentiation as well as tumour growth are tied to these processes, the studies suggest a new approach for both the preparation of induced pluripotent stem cells and the development of tumour treatments.

The results of the research were published in the journal Chemistry & Biology.

Cellular differentiation decides which functions can be assumed and carried out by cells in the body. Their precise regulation has a decisive influence on embryonic development and later also plays an essential role in maintaining the activity of organs. After toxic damage, among other things, it is important that cells can react appropriately to limit damage and regenerate the tissue. This requires close communication between the cells, which is controlled by numerous signal molecules. "Only when all the parts of a signal path are present, cells can react to the signals from the environment with a coordinated programme. If one of these components is missing, the proper cellular response is inhibited," explains Prof. Dr. Stefan W?lfl from Heidelberg University's Institute of Pharmacy and Molecular Biotechnology.

How cellular differentiation is controlled during embryonic development and in the mature organism significantly depends on the family of TGF?/BMP growth factors. Representatives of these specific signal molecules also participate in the genesis and development of tumour diseases. Through their work, the researchers have demonstrated that the cells themselves influence how sensitively they react to growth factor signals. This occurs through the availability of the complementary signal mediators within the cell adapting to the given situation. The amount of available regulatory SMAD proteins (R-Smad proteins) in the cell is controlled on the level of synthesis, but in particular through the control of their degradation. This is performed by a special control system present in every cell. This ubiquitin proteasome system makes it possible for cellular proteins to be degraded in a controlled manner.

Earlier research already demonstrated that the degradation of activated R-Smad proteins occurs through the ubiquitin proteasome system, resulting in termination of the signals. "Our results now prove that the reservoir of non-activated R-SMAD signal mediators is also strictly controlled. This prevents corresponding external signals from activating an internal programme," says Prof. W?lfl. "For example, if growing tumour cells are dependent on this signal, these cells could be kept from surviving and cell death may even occur if the signal mediators could be deliberately removed." According to Prof. W?lfl, R-Smad proteins are also important mediators in cellular differentiation. "Reducing or removing these signal mediators from stem cells would cause them to no longer react to differentiation signals, so they would retain their stem cell properties as a result."

In their experiments, the researchers worked with a variant of the natural product indirubin that they chemically synthesised. The studies showed that the indirubin derivative led to a degradation of the R-Smad proteins in human cells. Thus, the signals transmitted by the TGF?/BMP growth factors are blocked. In this procedure, the indirubin variant intervenes in various processes that all contribute to depleting the concentration of R-Smad proteins in the cell. In particular, the activity of specific regulating enzymes called ubiquitin proteases is diminished, which protect proteins from degradation in the ubiquitin proteasome system.

The research was funded by the Federal Ministry of Education and Research (BMBF) within a joint research project focussed on medical system biology. The research team at the Institute of Pharmacy and Molecular Biotechnology of Heidelberg University collaborated with scientists from the University of Kaiserslautern and the Jena University Hospital as well as the Heidelberg University Hospital's Institute of Human Genetics.

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The above story is reprinted from materials provided by Heidelberg, Universit?t.

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Journal Reference:

  1. Xinlai Cheng, Hamed Alborzinia, Karl-Heinz Merz, Herbert Steinbeisser, Ralf Mrowka, Catharina Scholl, Igor Kitanovic, Gerhard Eisenbrand, Stefan W?lfl. Indirubin Derivatives Modulate TGF?/BMP Signaling at Different Levels and Trigger Ubiquitin-Mediated Depletion of Nonactivated R-Smads. Chemistry & Biology, 2012; 19 (11): 1423 DOI: 10.1016/j.chembiol.2012.09.008

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/sqeQVMq_zNw/121130110554.htm

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VINTAGE: The Original Batmobile Up For Auction At Barrett-Jackson

The one-and-only original Batmobile from the 1960s TV series Batman is being offered by its creator, the legendary customizer George Barris, at Barrett-Jackson?s Scottsdale collector-car auction in January.

Barris has owned the famous Batmobile for nearly a half century, and this will be the first time the authentic TV car has ever been offered for sale.

This is the 1955 Lincoln Futura concept car that was heavily modified by Barris, known as the ?King of Kustomizers,? to become the original Batmobile in the campy Batman series, which ran from 1966 to 1968, starring Adam West in the title role and Burt Ward as Robin.

George Barris, who designed and built a number of famous cars for TV shows, has kept the Batmobile in his personal collection. (Photo: Barris Kustoms) The Batmobile is scheduled to cross the block during the ?prime-time? evening sale on Saturday, January 19. The iconic piece of TV history remains in excellent original condition, and the sale includes memorabilia and documentation from Barris's personal archives.

?The 1966 Batmobile by George Barris is one of the most famous Hollywood cars in history and it has become a true icon that has been carried from generation to generation of Batmobiles to follow,? said Craig Jackson, chairman and CEO of Barrett-Jackson. ?This vehicle not only marks the significant Bat logo that sits on the middle of its door, but a time in television history where they defied the odds of making a car the real star of the show.?

In August 1965, the producers of the upcoming Batman series approached Barris with a proposition. Could he and his customizing crew create a convincing Batmobile for the new show? There was just one catch: it had to be completed and ready for studio work in less than three weeks.

It so happened that Barris was in possession of the 1955 Lincoln Futura concept car that seemed made to order, which he had purchased several years earlier from Ford for a total of one dollar. The 19-foot-long, two-seat, bubble-topped prototype was hand-built in 1954 by Ghia Body Works in Turin, Italy, and unveiled at the Chicago Auto Show. It was promoted by Ford as a test bed for future technology.

It took Barris and his crew just 15 days and $15,000 to transform the Futura into the Batmobile. Among its exotic features is the wide array of faux Bat gadgets that turned the Batmobile into a make-believe crime fighter.

Among them: Cable Cutter Blade, Bat Ray Projector, Batscope, Bat Eye Switch, Police Band Cut-In Switch, Automatic Tire Inflation Device, Remote Batcomputer, Emergency Bat Turn Lever, Anti-Fire Activator, Bat Smoke, Bat Photoscope and, of course, the famous Batphone.

?There are only a few things in life that are able to capture the soul of an era, and the Batmobile by George Barris did exactly that,? said Steve Davis, president of Barrett-Jackson.

The 42nd annual Barrett-Jackson Scottsdale auction takes place at WestWorld from Jan. 13-20, with live coverage on SPEED TV. For information and tickets, see Barrett-Jackson.com.

Bob Golfen, Automotive Editor for SPEED.com, is a veteran auto writer based in Phoenix, Arizona, with a passion for collector cars, car culture and the automotive lifestyle. SPEED.com fans can email Bob Golfen at

Source: http://automotive.speedtv.com/article/vintage-the-original-batmobile-up-for-auction-at-barrett-jackson/

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Source: http://www.bucksandspurs.com/blog/cardy-uggs-they-are-really-the-consumer-which-will-develop-into-to-use-to-get-you-legal-help-you-always

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Keenly Followed Online Social Rating Community Thenumber1.com Throws Lights on Common Man's Opinion Pertaining to World Politics

Thenumber1.com, a popular social rating website, is quickly emerging as preferred platform for common people to express their independent stand about the most critical issues of world politics. This website has been introducing interesting social rating competitions covering a wide array of topics, since the launch of the website few months ago.

(PRWEB) November 30, 2012

After making an impact on its members with numerous fun filled social rating competitions, Thenumber1.com has just come up with a more serious competition on the hottest issues of world politics. This social rating website was created just a couple of months ago, and is already a popular online destination for the younger generation of internet users. It may be recalled that some of the competitions like top villain looks, rate my moustache, rate my cloth, etc. has received tremendous applause from the members of the website. With the introduction of the new competition on the hottest issues of world politics, many members are now using this community to express their opinion on these issues.

According to the new competition in Thenumber1.com, the most relevant issues of world politics includes NATO withdrawal from Afghanistan, Independence of Kashmir, US pullout from Iraq, Israel's attack on Gaza, etc. Amongst all these, the topic of NATO's withdrawal from Afghanistan has sparked a lot of interest amongst the members of the program. One may recall that NATO forces have been deployed throughout Afghanistan since the 9/11 terror attacks. Apart from allowing members to post their opinion on this debated political issue, Thenumber1.com has also published a brief post describing reasons for and against the withdrawal of NATO forces from Afghanistan.

Thenumber1.com's increasing popularity as a social rating website can be attributed to several features that are not available in most other similar websites. Social sharing, aggregate rating scheme, a comprehensive data model, and an advanced Graphical User Interface are the top factors that make this website the favorite online destination of thousands off people across the globe. When asked about the latest competition in their website, a senior official from Thenumber1.com said, "It is never easy for a common man to express his/her independent opinion on these political issues. That's the exact reason behind creating this competition".

Jonathan, Livne
elobby Ltd
972-72-2508688
Email Information

Source: http://news.yahoo.com/keenly-followed-online-social-rating-community-thenumber1-com-210050941.html

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Slovenia police clash with protesters ahead of vote

LJUBLJANA (Reuters) - Police used water canon to break up rock-throwing protesters in Slovenia's capital on Friday after a rally against budget cuts and alleged corruption turned violent two days ahead of a presidential election.

Officers said it was the first time they had used that level of crowd control since the country's independence from Yugoslavia in 1991 and 15 people, mostly policemen, were injured.

Thousands of Slovenians took to the streets in Ljubljana and six other cities in the financially troubled euro zone country, the latest in a series of protests.

"I'm protesting against the government because they are destroying our state, our educational, health and social systems. We have to show that we are against them and that they are not untouchable," a 47-year-old engineer Ziva Brcar told Reuters.

Some members of the crowd started throwing granite blocks and firecrackers at police in the capital, where about 30 people were arrested, said police.

Slovenia, which joined the euro zone in 2007 when it was the fastest-growing economy in the bloc, was badly hit by the global crisis due to its dependency on exports.

It is now in recession and struggling with weak exports, a fall in domestic spending due to budget cuts and increasing unemployment, while local banks are hit by rising bad loans.

The conservative government of Prime Minister Janez Jansa this year cut all public sector wages and most social benefits in order to reduce the budget deficit to 4.2 percent of GDP from 6.4 percent last year.

It plans further budget cuts in 2013 to bring the deficit to about 3 percent of GDP, normally the maximum level allowed for euro zone members.

The country holds a presidential election on Sunday with former centre-left prime minister Borut Pahor, who advocates a need for cooperation between the government and the opposition, expected to beat the incumbent centre-left president Danilo Turk.

The president, who has a five year mandate, is mostly a ceremonial figure.

Prime Minister Janez Jansa on Thursday called upon citizens to keep demonstrations peaceful.

"The situation is serious but there is no need to give up. We have all the potential to overcome the crisis by ourselves," he said in a statement.

(Editing by Greg Mahlich)

Source: http://news.yahoo.com/slovenia-police-clash-protesters-ahead-vote-233801737--business.html

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Jennifer Lee to direct Disney's animated "Frozen"

LOS ANGELES (TheWrap.com) - Jennifer Lee has been chosen to co-direct, along with "Tarzan's" Chris Buck, Disney's upcoming animated 3D film "Frozen," the company said Thursday.

Lee was a co-writer on the recent animated film "Wreck-It Ralph." She also contributed to the "Frozen" screenplay.

The toon, to be voiced by Kristen Bell and Idina Menzel, is about an optimist who embarks on an epic journey with a mountain man and his reindeer to stop her sister, a Snow Queen who's put an icy spell on her kingdom.

Lee's other credits include the screen adaptation of John Steinbeck's "The Acts of King Arthur and His Noble Knights," which is being produced by Troika Pictures.

Peter Del Vecho, the producer of "Frozen," said in a statement that Lee has "a real connection to the film and creates dynamic and relatable characters. Her sense of comedy, adventure and story structure paired with Chris Buck's vast experience and incredible instincts create an ideal situation for this film."

"Frozen" is slated for a November 27, 2013 release. The film will feature original music from "The Book of Mormon" composer Robert Lopez and "In Transit" composer Kristen Anderson-Lopez.

Source: http://news.yahoo.com/jennifer-lee-direct-disneys-animated-frozen-202508967.html

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What's Past is Prologue: a look inside the future of Lockheed Martin

DNP What's Past is Prologue A Look Inside the Future of Lockheed Martin

I receive a terse invite from Lockheed Martin that asks me to take a "glimpse into the future," but it doesn't mention whose future it is. I could write about what I know of the American defense contractor on the back of a postage stamp, but a cursory Google search fills in some of the blanks. The company reportedly receives around 7 percent of the US military budget on its own - and with that, my imagination runs rampant about what I'm likely to see. Dreaming of playing with laser pistols, intelligent cyborgs and giant robots, I tell them I'm coming.

A few days later, I turn up at the Honourable Artillery Company in London's glitzy financial district, a miniature castle that's dwarfed by the gleaming skyscrapers that surround it. In a way, the landscape is telling, since the occupants of those buildings can shoulder some of the blame for the current financial crisis - while across the street, Lockheed Martin is preparing its cost-cutting response.

Two hulking vehicles guard the entrance off a small courtyard, and through a window I see a plush room full of red velvet and leather, stuffed with computers and pensive, well-dressed operators. I wonder if I'm being vetted as I amble inside, my now-sodden socks and matted hair marking me out as unthreatening -- just as long as I promise not to get out my camera. As I'm ushered inside and the tour begins, I'm expecting to see jetpacks and robots, but the reality is much different. Not even this industry is immune to the world's financial problems, and my tour would reveal that its future lies decidedly in our past.

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